A Web Tool for Consensus Gene Regulatory Network Construction

Sarkar, Chiranjib and Parsad, Rajender and Mishra, Dwijesh C. and Rai, Anil (2021) A Web Tool for Consensus Gene Regulatory Network Construction. Frontiers in Genetics, 12. ISSN 1664-8021

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Abstract

Gene regulatory network (GRN) construction involves various steps of complex computational steps. This step-by-step procedure requires prior knowledge of programming languages such as R. Development of a web tool may reduce this complexity in the analysis steps which can be easy accessible for the user. In this study, a web tool for constructing consensus GRN by combining the outcomes obtained from four methods, namely, correlation, principal component regression, partial least square, and ridge regression, has been developed. We have designed the web tool with an interactive and user-friendly web page using the php programming language. We have used R script for the analysis steps which run in the background of the user interface. Users can upload gene expression data for constructing consensus GRN. The output obtained from analysis will be available in downloadable form in the result window of the web tool.

Item Type: Article
Subjects: West Bengal Archive > Medical Science
Depositing User: Unnamed user with email support@westbengalarchive.com
Date Deposited: 25 Jan 2023 10:55
Last Modified: 29 Jun 2024 12:25
URI: http://article.stmacademicwriting.com/id/eprint/74

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