Biochemical Markers Present in a Population Susceptible to Suffering From Metabolic Syndrome

OBJECTIVE: To determine the prevalence of metabolic syndrome (SM) according to Adult Treatment Panel III ATPIII and its relation with uric acid concentration and C-reactive protein, in people aged from 45 to 60 years old from the Getsemaní neighborhood of Cartagena city, Colombia.

MATERIALS AND METHODS: Type of study: Observational, Descriptive-Correlation. Population of 802 inhabitants from the Getsemaní neighborhood of Cartagena city. We analyzed 302 inhabitants from a random sample with 95% confidence level and 5% of error level. The ATP III diagnostic criteria were applied, the applied instrument had basic data about the general context (social, demographic, economic aspects, family history, work activity and its physical characteristics: weight, waist circumference, blood pressure, calculation of BMI), as well diagnostic tests as: glycaemia, total cholesterol, triglycerides, HDLc, LDLc, uric acid, ultrasensitive C-reactive protein.

RESULTS: The population susceptible to metabolic syndrome presented a prevalence of 18%. The most prevalent metabolic syndrome factor was abdominal obesity with 85%, followed by an increase in triglycerides by 76%.

CONCLUSION: When applying the ATP III criteria, the prevalence of metabolic syndrome was considered high. There was no significant association of C-reactive protein values with the possibility of developing metabolic syndrome in both men and women, but uric acid results were found to be correlated in the group of women susceptible to MS with a p = 0.0022.