Binnenmars, Heleen and Idzerda, Herman H. D. and Tan, Hanno L. and Linssen, Gerard C. M. (2012) Ventricular Tachycardia during Treatment with Modafinil for Narcolepsy: A Case Report. International Journal of Clinical Medicine, 03 (06). pp. 513-517. ISSN 2158-284X
IJCM20120600011_93455792.pdf - Published Version
Download (3MB)
Abstract
Pharmacological treatment of narcolepsy is complex. We reported a case of recurrent episodes of polymorphic ventricular tachycardia attributed to the use of modafinil, a recently approved wake-promoting agent for narcolepsy and shift work sleep disorder. Modafinil is also approved as adjunctive treatment of obstructive sleep apnea/hypopnea syndrome. While the exact mechanism of action for modafinil is not known, central dopamine receptors seem to play an essential role. Adverse influences on the electrocardiogram (ECG) or drug-related cardiac arrhythmias are rarely reported, but are considered as clinically important.
Item Type: | Article |
---|---|
Subjects: | West Bengal Archive > Medical Science |
Depositing User: | Unnamed user with email support@westbengalarchive.com |
Date Deposited: | 11 Feb 2023 08:26 |
Last Modified: | 17 Jul 2024 09:54 |
URI: | http://article.stmacademicwriting.com/id/eprint/37 |