Ventricular Tachycardia during Treatment with Modafinil for Narcolepsy: A Case Report

Binnenmars, Heleen and Idzerda, Herman H. D. and Tan, Hanno L. and Linssen, Gerard C. M. (2012) Ventricular Tachycardia during Treatment with Modafinil for Narcolepsy: A Case Report. International Journal of Clinical Medicine, 03 (06). pp. 513-517. ISSN 2158-284X

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Abstract

Pharmacological treatment of narcolepsy is complex. We reported a case of recurrent episodes of polymorphic ventricular tachycardia attributed to the use of modafinil, a recently approved wake-promoting agent for narcolepsy and shift work sleep disorder. Modafinil is also approved as adjunctive treatment of obstructive sleep apnea/hypopnea syndrome. While the exact mechanism of action for modafinil is not known, central dopamine receptors seem to play an essential role. Adverse influences on the electrocardiogram (ECG) or drug-related cardiac arrhythmias are rarely reported, but are considered as clinically important.

Item Type: Article
Subjects: West Bengal Archive > Medical Science
Depositing User: Unnamed user with email support@westbengalarchive.com
Date Deposited: 11 Feb 2023 08:26
Last Modified: 17 Jul 2024 09:54
URI: http://article.stmacademicwriting.com/id/eprint/37

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