Evaluation of Wound Healing Activity of Aqueous Extract of Chromolaena odorata on Wistar Rats

Panda, Subham Kumar and Mishra, Sunita and Ray, B. and Sharma, V. G. S. (2024) Evaluation of Wound Healing Activity of Aqueous Extract of Chromolaena odorata on Wistar Rats. UTTAR PRADESH JOURNAL OF ZOOLOGY, 45 (17). pp. 98-105. ISSN 0256-971X

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Abstract

Introduction: A wound can be defined as any physical injury or break in the skin or underlying tissues caused by trauma, surgery, or various medical conditions. Wound healing is a complex and dynamic biological process that occurs in response to injury or damage to the skin or underlying tissues. Medecinal plant have been reported to show wound healing Potential via angiogenesis activation of NF-κB, favoring pro-inflammatory cytokines, increased expression of induciblenitric oxide syntheses (iNOS) and alpha 1 type 1 collagen, and anti-oxidant activity.

Materials and Methods: The Present Research work Conclude the wound healing potential of standard and aqueous extract of Chromolaena odorata was studied on Wistar rat excision wound model.

Results and Discussion: The topical application of standard (soframycin) showed a significantly faster wound contraction rate (70.58%) on 15th post-operative day as compared to non-treated group (33.33%).

Conclusion: The topical application of standard (soframycin) showed a significantly faster wound contraction rate (70.58%) on 15th post-operative day as compared to non-treated group (33.33%). Aqueous extract of Chromolaena odorata showed wound contraction rate of (61.66%) on 15th post-operative day as compared to non-treated group (33.33%).

Item Type: Article
Subjects: West Bengal Archive > Biological Science
Depositing User: Unnamed user with email support@westbengalarchive.com
Date Deposited: 14 Aug 2024 06:39
Last Modified: 14 Aug 2024 06:39
URI: http://article.stmacademicwriting.com/id/eprint/1418

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