Serum C-reactive protein and erythrocyte sedimentation rate changes in children after adenotonsillectomy

Mousavi Aghdas, Mehrnoosh and Shahidi, Nikzad and Abdollahi Fakhim, Shahin (2021) Serum C-reactive protein and erythrocyte sedimentation rate changes in children after adenotonsillectomy. Medical Journal of Tabriz University of Medical Sciences and Health Services, 42 (6). pp. 684-691. ISSN 1608-5671

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Abstract

Background: Sleep-disordered breathing is a common problem in children and is associated with increased cardiovascular morbidity. The circulating level of C-reactive protein, a pro-inflammatory protein, is associated with increased risk for atherosclerosis. The aim of this study was the comparison of C-reactive protein level and erythrocyte sedimentation rate in children with tonsillar hypertrophy before and after adenotonsillectomy.

Methods: All patients aged between 4 to 10 years who had underwent adenotonsillectomy due to obstructive sleep apnea were enrolled. Serum C-reactive protein and erythrocyte sedimentation rate were measured before and after adenotonsillectomy. Data were analyzed with SPSS version 19.

Results: In this study, 384 patients were enrolled. The average age of the patients was 6.7 years. The C-reactive protein level in 91 patients (23.7 %) was decreased and in 286 patients (74.5%) did not change and in 7 patients (1.8%) it was increased. Decreasing serum C-reactive protein level and erythrocyte sedimentation rate was statistically significant after adenotonsillectomy (P-value < 0.05).

Conclusion: Obstructive sleep apnea induces a systemic inflammatory response so frequently associated with an increase in serum C-reactive protein and erythrocyte sedimentation rate that is reversible with surgery and if left untreated may lead to cardiovascular morbidity.

Item Type: Article
Subjects: West Bengal Archive > Medical Science
Depositing User: Unnamed user with email support@westbengalarchive.com
Date Deposited: 13 Jun 2023 06:12
Last Modified: 06 Jul 2024 07:42
URI: http://article.stmacademicwriting.com/id/eprint/1051

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